New injectable materials to treat gum disease and bone loss
Novel Injectable Biomaterials for Periodontitis
This study is working on new injectable treatments for gum disease that can help heal your gums and bones, making it easier for you to keep your teeth healthy and strong.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Iowa NIH-funded |
| Lab location | 1 site (Iowa City, United States) |
| Project ID | NIH-11088276 on NIH RePORTER |
What this research studies
This research focuses on developing innovative injectable biomaterials to treat periodontitis, a common gum disease that can lead to significant bone loss and tooth loss in adults. The approach combines tissue engineering with the use of specific metabolites and antimicrobial agents to enhance bone regeneration and reduce inflammation. By collaborating with experienced periodontists, the research aims to create effective treatments that can be directly applied to affected areas, potentially improving patient outcomes. The study will also explore the use of hydrogels to deliver these treatments locally, targeting the root causes of periodontitis.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 30 years old who are experiencing periodontitis or related bone loss.
Not a fit: Patients with mild gum disease or those under 30 years old may not receive significant benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for periodontitis, reducing the risk of tooth loss and improving overall oral health.
How similar studies have performed: Previous research has shown promise in using biomaterials and tissue engineering for periodontal treatments, indicating a potential for success in this novel approach.
Where this research is happening
Iowa City, United States
- University of Iowa — Iowa City, United States (Active)
Researchers
- Principal investigator: Sun, Hongli — University of Iowa
- Study coordinator: Sun, Hongli
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.