New imaging tool for detecting eye diseases
Official title: Ultra-high speed AO-OCT clinical system to image ganglion cells and microglia
Funded at Physical Sciences, INC · NIH-10705315 · Data updated 2026-11-12
This study is working on a new imaging tool that helps doctors see important cells in the eye more clearly, which could lead to better diagnosis and treatment for people with glaucoma and diabetic retinopathy.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Physical Sciences, INC NIH-funded |
| Lab location | 1 site (Andover, United States) |
| Project start | September 30, 2022 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $841,839 |
| NIH project number | 5R44EY034409-02 |
| Project ID | NIH-10705315 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with glaucoma or diabetic retinopathy, particularly those at various stages of disease severity.
✕Less likely to help
Patients with no history of retinal diseases or those who do not have access to the clinical sites may not benefit from this research.
What this research studies
This research aims to develop an advanced imaging system that can accurately visualize retinal ganglion cells and microglia in live human eyes. By utilizing a novel adaptive optics approach, the tool will enhance the diagnosis and monitoring of conditions like glaucoma and diabetic retinopathy. The system will be tested in clinical settings, allowing for the collection of valuable patient data to identify specific biomarkers associated with these eye diseases. This innovative technology seeks to improve the precision of retinal disease assessments and treatment strategies.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate detection of retinal diseases, potentially improving patient outcomes.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for retinal assessments, indicating a potential for success with this novel approach.
Where this research is happening
-
Physical Sciences, INC
Andover, United States Active
Researchers
- Principal investigator: Mujat, Mircea — Physical Sciences, INC
- Study coordinator: Mujat, Mircea
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.