New imaging tool for detecting eye diseases

Ultra-high speed AO-OCT clinical system to image ganglion cells and microglia

['FUNDING_SBIR_2'] · PHYSICAL SCIENCES, INC · NIH-10705315

This study is working on a new imaging tool that helps doctors see important cells in the eye more clearly, which could lead to better diagnosis and treatment for people with glaucoma and diabetic retinopathy.

Quick facts

Phase['FUNDING_SBIR_2']
Study typeNih_funding
SexAll
SponsorPHYSICAL SCIENCES, INC (nih funded)
Locations1 site (ANDOVER, UNITED STATES)
Trial IDNIH-10705315 on ClinicalTrials.gov

What this research studies

This research aims to develop an advanced imaging system that can accurately visualize retinal ganglion cells and microglia in live human eyes. By utilizing a novel adaptive optics approach, the tool will enhance the diagnosis and monitoring of conditions like glaucoma and diabetic retinopathy. The system will be tested in clinical settings, allowing for the collection of valuable patient data to identify specific biomarkers associated with these eye diseases. This innovative technology seeks to improve the precision of retinal disease assessments and treatment strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with glaucoma or diabetic retinopathy, particularly those at various stages of disease severity.

Not a fit: Patients with no history of retinal diseases or those who do not have access to the clinical sites may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier and more accurate detection of retinal diseases, potentially improving patient outcomes.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for retinal assessments, indicating a potential for success with this novel approach.

Where this research is happening

ANDOVER, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Diabetes Mellitus, diabetes, Disease, Disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.