New imaging technology to track brain tumor growth and invasion
Interleaved 1H/23Na imaging for invasive and proliferative phenotypes of brain tumors
['FUNDING_R01'] · YALE UNIVERSITY · NIH-11030782
This study is testing a new imaging technique to help doctors better understand and track the different types of brain tumors, especially glioblastoma, by looking at their unique chemical properties, which could lead to better treatment options for patients.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | YALE UNIVERSITY (nih funded) |
| Locations | 1 site (NEW HAVEN, UNITED STATES) |
| Trial ID | NIH-11030782 on ClinicalTrials.gov |
What this research studies
This research focuses on developing advanced imaging technology to differentiate and monitor invasive and proliferative phenotypes of brain tumors, particularly glioblastoma multiforme (GBM). Current imaging methods are unable to effectively track these critical cancer characteristics, which contribute to treatment failure. By utilizing 1H/23Na magnetic resonance spectroscopic imaging (MRSI), the study aims to identify unique chemical and electrical properties of cancer cells, specifically their altered acidity and salinity. This innovative approach could provide valuable insights into tumor behavior and guide more effective treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with glioblastoma multiforme who are undergoing treatment.
Not a fit: Patients with brain tumors other than glioblastoma multiforme may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring of brain tumors and more effective treatment options for patients with GBM.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques to study cancer behavior, suggesting that this approach may yield significant insights.
Where this research is happening
NEW HAVEN, UNITED STATES
- YALE UNIVERSITY — NEW HAVEN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HYDER, DEWAN SYED FAHMEED — YALE UNIVERSITY
- Study coordinator: HYDER, DEWAN SYED FAHMEED
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: anti-cancer therapy