New imaging technology to track brain tumor growth and invasion
Official title: Interleaved 1H/23Na imaging for invasive and proliferative phenotypes of brain tumors
Funded at Yale University · NIH-11030782 · Data updated 2026-11-12
This study is testing a new imaging technique to help doctors better understand and track the different types of brain tumors, especially glioblastoma, by looking at their unique chemical properties, which could lead to better treatment options for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | March 8, 2023 |
| Project end | February 28, 2027 |
| Funding year | 2025 |
| Award (this year) | $564,399 |
| NIH project number | 5R01CA280871-03 |
| Project ID | NIH-11030782 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with glioblastoma multiforme who are undergoing treatment.
✕Less likely to help
Patients with brain tumors other than glioblastoma multiforme may not receive direct benefits from this research.
What this research studies
This research focuses on developing advanced imaging technology to differentiate and monitor invasive and proliferative phenotypes of brain tumors, particularly glioblastoma multiforme (GBM). Current imaging methods are unable to effectively track these critical cancer characteristics, which contribute to treatment failure. By utilizing 1H/23Na magnetic resonance spectroscopic imaging (MRSI), the study aims to identify unique chemical and electrical properties of cancer cells, specifically their altered acidity and salinity. This innovative approach could provide valuable insights into tumor behavior and guide more effective treatment strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring of brain tumors and more effective treatment options for patients with GBM.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques to study cancer behavior, suggesting that this approach may yield significant insights.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Hyder, Dewan Syed Fahmeed — Yale University
- Study coordinator: Hyder, Dewan Syed Fahmeed
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.