New imaging technology to help surgeons locate and remove tumors more effectively

Dual orthogonal fluorescent protease sensors for image guided surgery

NIH-funded research Stanford University · NIH-10457944

This study is testing a new tool that helps surgeons see tumors better during surgery, which could make it easier to remove all the cancer and lower the chances of it coming back, and it's designed for patients having surgery for cancer.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionStanford University NIH-funded
Lab location1 site (Stanford, United States)
Project IDNIH-10457944 on NIH RePORTER

What this research studies

This research focuses on developing advanced fluorescent sensors that can help surgeons identify tumors during surgery. By using specialized optical probes that react to specific enzymes found in the tumor environment, the technology aims to provide real-time imaging of cancerous tissues. This approach seeks to improve the accuracy of tumor removal and reduce the chances of cancer recurrence after surgery. Patients undergoing surgical treatment for cancer may benefit from this innovative imaging technique.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients undergoing surgical procedures for cancer treatment.

Not a fit: Patients who are not undergoing surgery or those with non-cancerous conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more precise tumor removals and lower rates of cancer recurrence for patients.

How similar studies have performed: Other research has shown promise in using optical imaging techniques for surgical guidance, indicating a potential for success with this novel approach.

Where this research is happening

Stanford, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions DiseaseDisorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.