New imaging technology for observing brain activity in adults

Massively parallel high-speed 3D functional photoacoustic computed tomography of the adult human brain

NIH-funded research California Institute of Technology · NIH-10906090

This study is testing a new imaging technique called 3D photoacoustic computed tomography (PACT) to help us see how the brain works in adults more quickly and accurately, which could lead to better ways to diagnose and understand brain disorders.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionCalifornia Institute of Technology NIH-funded
Lab location1 site (Pasadena, United States)
Project IDNIH-10906090 on NIH RePORTER

What this research studies

This research focuses on developing a groundbreaking imaging technique called 3D photoacoustic computed tomography (PACT) to visualize brain activity in adults. By utilizing this innovative method, researchers aim to achieve faster and more accurate imaging of neural activity compared to traditional methods like fMRI. The approach leverages the sensitivity of PACT to detect changes in blood flow related to brain function, providing insights into how the brain operates at a detailed level. Patients may benefit from this technology as it could lead to improved diagnostic capabilities and better understanding of brain disorders.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who may be experiencing neurological conditions or are healthy volunteers interested in brain research.

Not a fit: Patients with conditions that do not affect brain function or those under the age of 21 may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could significantly enhance the ability to diagnose and understand brain conditions, leading to better treatment options for patients.

How similar studies have performed: Previous research has shown promise in using photoacoustic imaging techniques, but this specific application in adult human brain imaging is relatively novel.

Where this research is happening

Pasadena, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.