New imaging technology for better liver cancer treatment

Hybrid virtual-MRI/CBCT: A new paradigm for image guidance in liver SBRT

['FUNDING_R01'] · UNIVERSITY OF MARYLAND BALTIMORE · NIH-10229488

This study is testing a new imaging system that combines virtual MRI and cone beam CT to help doctors better target liver tumors during radiation therapy, making treatment safer and more effective for patients with liver cancer.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MARYLAND BALTIMORE (nih funded)
Locations1 site (BALTIMORE, UNITED STATES)
Trial IDNIH-10229488 on ClinicalTrials.gov

What this research studies

This research focuses on developing a hybrid virtual-MRI and cone beam CT (CBCT) system to enhance image guidance during radiation therapy for liver cancer. By improving the accuracy of tumor localization, the study aims to reduce the high local failure rates and toxicity associated with current treatment methods. The approach seeks to provide a low-cost alternative to existing MRI machines, which are often too expensive for widespread use in clinics. Patients undergoing stereotactic body radiation therapy (SBRT) for liver cancer may benefit from this improved imaging technology.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients diagnosed with liver cancer who are considering or undergoing stereotactic body radiation therapy.

Not a fit: Patients with liver cancer who are not eligible for radiation therapy or those with advanced disease stages may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and safer treatment options for liver cancer patients.

How similar studies have performed: Previous studies have shown that improved imaging techniques can significantly enhance treatment outcomes in radiation therapy, indicating a promising potential for this novel approach.

Where this research is happening

BALTIMORE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Breast Cancer

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.