New imaging techniques to observe brain inflammation in Alzheimer's disease
Official title: Novel imaging biomarkers of neuroinflammation in Alzheimer's disease
Funded at University of Pennsylvania · NIH-11053855 · Data updated 2026-11-12
This study is looking at new ways to see how inflammation in the brain might be linked to the early stages of Alzheimer's disease, which could help doctors find better ways to diagnose and treat the condition sooner.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | December 15, 2024 |
| Project end | November 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $812,030 |
| NIH project number | 1R01AG091760-01 |
| Project ID | NIH-11053855 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals in the early stages of Alzheimer's disease or those at high risk for developing the condition.
✕Less likely to help
Patients with advanced Alzheimer's disease or other forms of dementia unrelated to neuroinflammation may not benefit from this research.
What this research studies
This research focuses on developing noninvasive imaging biomarkers to monitor neuroinflammation in the early stages of Alzheimer's disease (AD). By utilizing advanced techniques like deuterium-magnetic-resonance-spectroscopy (DMRS) and quantitative-exchanged-label-turnover MRS (qeltMRS), the study aims to explore the relationship between brain inflammation and the progression of AD. Patients may benefit from improved diagnostic tools that can detect changes in the brain associated with AD, potentially leading to earlier interventions.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic methods for Alzheimer's disease, allowing for earlier detection and treatment.
How similar studies have gone: Previous research has shown promise in using imaging techniques to study neuroinflammation, suggesting that this approach may yield valuable insights.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Haris, Mohammad — University of Pennsylvania
- Study coordinator: Haris, Mohammad
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.