New imaging techniques for detecting Lyme disease
Official title: ImmunoPET Probes for the Imaging of Lyme Disease
Funded at Hunter College · NIH-10931607 · Data updated 2026-11-12
This study is working on new imaging tools that can help doctors see Lyme disease more clearly in patients, making it easier to diagnose and treat the condition without needing invasive procedures.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Hunter College NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 19, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $556,751 |
| NIH project number | 5R01AI175417-02 |
| Project ID | NIH-10931607 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who have been diagnosed with Lyme disease or exhibit symptoms consistent with the condition.
✕Less likely to help
Patients who do not have Lyme disease or are not exhibiting any related symptoms may not benefit from this research.
What this research studies
This research focuses on developing innovative imaging probes that can help visualize Lyme disease in patients. By creating radiopharmaceuticals that target a specific protein found on the surface of the bacteria causing Lyme disease, the study aims to improve the accuracy of diagnosis and treatment. Patients may benefit from non-invasive imaging techniques that provide clearer insights into the presence and progression of the disease. The research involves synthesizing and testing these imaging agents in laboratory settings before moving to patient applications.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and timely diagnoses of Lyme disease, improving treatment outcomes for patients.
How similar studies have gone: Other research has shown promise in using imaging techniques for various diseases, suggesting potential success for this novel approach in Lyme disease.
Where this research is happening
-
Hunter College
New York, United States Active
Researchers
- Principal investigator: Zeglis, Brian Matthew — Hunter College
- Study coordinator: Zeglis, Brian Matthew
Related research
Other NIH-funded projects on the same topics.
-
Understanding why some people have ongoing symptoms after Lyme disease
A long-term study follows people diagnosed with acute Lyme disease to see who develops persistent symptoms and why, with care from a team of Lyme experts.
-
CSF Protein Map in Post-Treatment Lyme Disease
A short study to map proteins in spinal fluid of people who had Lyme disease and still feel sick after standard treatment, to understand what’s going on.
-
Lyme disease vaccine research aimed at preventing infection
Researchers are developing a Lyme disease vaccine by studying how the immune system responds to Borrelia burgdorferi and testing vaccine approaches to prevent illness.
-
Lyme disease brain health: tracking brain signals and blood clues after treatment
This study follows people with early Lyme disease and compares them to healthy volunteers to see how the brain and blood markers change over a year after starting antibiotics.
-
Lyme disease symptoms lingering after treatment may be driven by special bacterial fragments
A human-friendly look at a study exploring why some Lyme patients keep symptoms after antibiotics and whether tiny fragments from the bacteria are to blame.
-
Understanding Lyme disease immune signals to predict recovery after antibiotics
A research project at MIT aims to find immune biomarkers that tell which Lyme patients will recover after standard antibiotics and who might have lasting symptoms.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.