New imaging techniques for assessing heart plaque in patients
Dual-modality FLIm and PSOCT for intravascular imaging of plaque in patients
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA AT DAVIS · NIH-10907691
This study is exploring new ways to see the changes in heart artery plaques using special imaging tools, which could help doctors better understand and treat coronary artery disease during routine heart procedures.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA AT DAVIS (nih funded) |
| Locations | 1 site (DAVIS, UNITED STATES) |
| Trial ID | NIH-10907691 on ClinicalTrials.gov |
What this research studies
This research focuses on improving the understanding of coronary artery disease by developing advanced imaging techniques that can visualize the biochemical and structural changes in atherosclerotic plaques within the arteries. The study aims to combine two innovative imaging methods, Fluorescence Lifetime Imaging (FLIm) and Polarization Sensitive Optical Coherent Tomography (PSOCT), into a single catheter that can be used during routine heart procedures. By providing real-time insights into plaque characteristics, this approach could help doctors make more informed decisions about patient care and treatment options.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients undergoing procedures for coronary artery disease who have atherosclerotic plaques.
Not a fit: Patients without coronary artery disease or those not undergoing cardiac catheterization procedures may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better management and prevention of acute coronary syndromes in patients with coronary artery disease.
How similar studies have performed: Other research has shown promise with similar imaging techniques, indicating potential for significant advancements in understanding plaque dynamics.
Where this research is happening
DAVIS, UNITED STATES
- UNIVERSITY OF CALIFORNIA AT DAVIS — DAVIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MARCU, LAURA — UNIVERSITY OF CALIFORNIA AT DAVIS
- Study coordinator: MARCU, LAURA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.