New imaging technique to identify pain after hip replacement surgery

Novel PET/MR Imaging Approach for Persistent Postsurgical Pain Following Joint Replacement

NIH-funded research University of Wisconsin-Madison · NIH-10914210

This study is testing a new imaging technique to help find out what's causing ongoing pain after hip replacement surgery, so that patients can get better answers and care for their discomfort.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Wisconsin-Madison NIH-funded
Lab location1 site (Madison, United States)
Project IDNIH-10914210 on NIH RePORTER

What this research studies

This research focuses on developing a new imaging method using 18F-fluorodeoxyglucose PET/MRI to detect complications that cause persistent pain after total hip arthroplasty. The approach aims to overcome limitations of current imaging techniques, which struggle to accurately identify pain sources due to metal artifacts from prosthetic joints. By improving the sensitivity of imaging for detecting inflammation, this research seeks to provide better diagnostic tools for patients suffering from ongoing pain after surgery.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have undergone total hip arthroplasty and are experiencing persistent postsurgical pain.

Not a fit: Patients who have not had hip replacement surgery or those without persistent pain following the procedure may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate diagnoses and targeted treatments for patients experiencing persistent pain after hip replacement surgery.

How similar studies have performed: Previous studies using 18F-FDG PET/MRI for chronic pain syndromes have shown promising results, indicating potential success for this novel approach.

Where this research is happening

Madison, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.