New imaging technique to detect brain blood vessel issues through the eye
Novel retinal higher-order capillary hemodynamics imaging for detecting cerebral small vessel disease
['FUNDING_OTHER'] · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · NIH-11096192
This study is testing a new way to look at the health of your brain's blood vessels by examining the tiny blood vessels in your eyes, which could help detect cerebral small vessel disease earlier and more easily than regular MRI scans.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MIAMI SCHOOL OF MEDICINE (nih funded) |
| Locations | 1 site (CORAL GABLES, UNITED STATES) |
| Trial ID | NIH-11096192 on ClinicalTrials.gov |
What this research studies
This research focuses on improving the detection of cerebral small vessel disease (CSVD), a common condition that can lead to cognitive impairment and dementia. By developing a novel imaging technique that examines the retina, researchers aim to identify changes in blood flow within retinal capillaries, which may reflect the health of blood vessels in the brain. The study will utilize a high-speed, wide-field adaptive optics ophthalmoscope to capture detailed images of retinal blood flow dynamics. This approach could provide a less invasive and more sensitive method for monitoring CSVD compared to traditional MRI scans.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk for or diagnosed with cerebral small vessel disease, particularly those experiencing cognitive decline.
Not a fit: Patients with no signs of cerebral small vessel disease or those who do not have access to the imaging technology may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate detection of cerebral small vessel disease, potentially improving patient outcomes and treatment options.
How similar studies have performed: Previous research has shown promise in using retinal imaging to assess brain health, suggesting that this novel approach may build on established findings.
Where this research is happening
CORAL GABLES, UNITED STATES
- UNIVERSITY OF MIAMI SCHOOL OF MEDICINE — CORAL GABLES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WANG, JIANHUA — UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
- Study coordinator: WANG, JIANHUA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.