New imaging technique to detect and understand prostate cancer in men with metal implants
Official title: Novel 3D DWI for Detection and Characterization of Prostate Cancer in Men with Pelvic Metal Implants
Funded at Mayo Clinic Rochester · NIH-11109218 · Data updated 2026-11-12
This study is testing a new imaging technique to help doctors better see and understand prostate cancer in men who have metal implants in their pelvis, making it easier to make treatment decisions for those at higher risk.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | December 14, 2023 |
| Project end | November 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $183,475 |
| NIH project number | 7R21CA277138-02 |
| Project ID | NIH-11109218 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are men over 50 years old who have been diagnosed with prostate cancer and have pelvic metal implants.
✕Less likely to help
Patients without prostate cancer or those who do not have pelvic metal implants may not benefit from this research.
What this research studies
This research focuses on improving the detection and characterization of prostate cancer using a novel 3D diffusion-weighted imaging (DWI) technique, specifically designed for men who have pelvic metal implants. The study aims to address the challenges posed by these implants, which can distort MRI images and hinder accurate diagnosis. By enhancing imaging capabilities, the research seeks to provide better guidance for treatment decisions in men at high risk for prostate cancer, particularly those with rising PSA levels or undergoing active surveillance. The approach involves advanced imaging technology to ensure clearer visualization of prostate lesions, which is crucial for effective disease management.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and better treatment options for men with prostate cancer, particularly those with pelvic metal implants.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for cancer detection, but this specific approach for men with metal implants is relatively novel.
Where this research is happening
-
Mayo Clinic Rochester
Rochester, United States Active
Researchers
- Principal investigator: Madhuranthakam, Ananth J — Mayo Clinic Rochester
- Study coordinator: Madhuranthakam, Ananth J
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.