NIH-funded research R21 grant

New imaging technique to detect and understand prostate cancer in men with metal implants

Official title: Novel 3D DWI for Detection and Characterization of Prostate Cancer in Men with Pelvic Metal Implants

Funded at Mayo Clinic Rochester · NIH-11109218 · Data updated 2026-11-12

This study is testing a new imaging technique to help doctors better see and understand prostate cancer in men who have metal implants in their pelvis, making it easier to make treatment decisions for those at higher risk.

More Prostate Cancer research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionMayo Clinic Rochester
NIH-funded
Lab location1 site (Rochester, United States)
Project startDecember 14, 2023
Project endNovember 30, 2026
Funding year2024
Award (this year)$183,475
NIH project number7R21CA277138-02
Project IDNIH-11109218 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are men over 50 years old who have been diagnosed with prostate cancer and have pelvic metal implants.

Less likely to help

Patients without prostate cancer or those who do not have pelvic metal implants may not benefit from this research.

What this research studies

This research focuses on improving the detection and characterization of prostate cancer using a novel 3D diffusion-weighted imaging (DWI) technique, specifically designed for men who have pelvic metal implants. The study aims to address the challenges posed by these implants, which can distort MRI images and hinder accurate diagnosis. By enhancing imaging capabilities, the research seeks to provide better guidance for treatment decisions in men at high risk for prostate cancer, particularly those with rising PSA levels or undergoing active surveillance. The approach involves advanced imaging technology to ensure clearer visualization of prostate lesions, which is crucial for effective disease management.

Why it matters

Potential benefit: If successful, this research could lead to more accurate diagnoses and better treatment options for men with prostate cancer, particularly those with pelvic metal implants.

How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for cancer detection, but this specific approach for men with metal implants is relatively novel.

Where this research is happening

  • Mayo Clinic Rochester
    Rochester, United States
    Active

Researchers

  • Principal investigator: Madhuranthakam, Ananth J — Mayo Clinic Rochester
  • Study coordinator: Madhuranthakam, Ananth J

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.