NIH-funded research R01 grant

New ideas to balance energy after exercise to help with weight loss

Official title: Novel Mechanisms Promoting Energy Intake Compensation in Response to Aerobic and Resistance Exercise

Funded at Arkansas Colleges of Health Education · NIH-11433555 · Data updated 2026-11-12

This study looks at why people don’t lose as much weight as expected when they exercise and explores how both cardio and strength training affect appetite and energy balance.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionArkansas Colleges of Health Education
NIH-funded
Lab location1 site (Fort Smith, United States)
Project startSeptember 1, 2026
Project endMay 31, 2031
Funding year2026
Award (this year)$646,459
NIH project number1R01DK148868-01
Project IDNIH-11433555 on NIH RePORTER

Who could benefit from this research

Could help

Adults who are overweight or at risk of obesity and are considering or already engaging in aerobic and resistance exercise.

Less likely to help

Individuals not following an exercise program or without weight-management goals may see limited relevance.

What this research studies

If you’re trying to lose weight through exercise, this research aims to understand why your body might compensate by eating more. Researchers will compare aerobic and combined aerobic-plus-resistance workouts to see how energy intake changes in response to different exercise programs. The study uses adults and will monitor diet, activity, and body changes to uncover mechanisms behind appetite and energy balance after exercise. The goal is to inform better lifestyle strategies for sustainable weight management.

Why it matters

Potential benefit: If successful, findings could lead to more effective exercise programs and guidelines for reducing overeating after workouts.

How similar studies have gone: Previous work suggests energy intake can increase with exercise, but results are mixed when comparing aerobic to combined exercise.

Where this research is happening

  • Arkansas Colleges of Health Education
    Fort Smith, United States
    Active

Researchers

  • Principal investigator: Flack, Kyle David — Arkansas Colleges of Health Education
  • Study coordinator: Flack, Kyle David

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.