New grafts to treat severe burn injuries
PHMB-Impregnated Acellular Biologic Grafts for Treatment of Third-Degree Burns
This study is testing a new type of skin graft that helps heal deep burns by not only supporting new tissue growth but also releasing medicine to prevent infections, making it a great option for people with serious burn injuries.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Bioaesthetics Corporation NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10912770 on NIH RePORTER |
What this research studies
This research focuses on developing a drug-eluting acellular dermal graft designed for the single-stage reconstruction of full-thickness burns. It aims to improve healing outcomes for burn patients by providing a scaffold that supports tissue regeneration while simultaneously releasing therapeutic agents to prevent infections, which are common complications in burn healing. The graft is created using a patented method that removes cells and immunogens from donor tissue, allowing for better integration with the patient's body. The project is currently assessing the feasibility of this innovative approach in treating third-degree burns.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from third-degree burns requiring medical intervention.
Not a fit: Patients with minor burns or those who do not require surgical intervention may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly enhance healing and reduce complications for patients with severe burn injuries.
How similar studies have performed: Other research has shown promise in using acellular grafts for wound healing, but this specific approach with drug-eluting properties is relatively novel.
Where this research is happening
Durham, United States
- Bioaesthetics Corporation — Durham, United States (Active)
Researchers
- Principal investigator: Blum, Juliana Lyn — Bioaesthetics Corporation
- Study coordinator: Blum, Juliana Lyn
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.