NIH-funded research Sbir 1 grant

New epidural leads to relieve chronic arm and neck pain

Official title: Thin, Softening Epidural Leads for Chronic Arm and Neck Pain

Funded at Backstop Neural, INC. · NIH-11006736 · Data updated 2026-11-12

This study is testing a new, softer type of epidural stimulation device to help people with chronic arm and neck pain feel better by making it easier to implant and more effective for treating their pain.

More Neck Pain research and trials

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionBackstop Neural, INC.
NIH-funded
Lab location1 site (Dallas, United States)
Project startAugust 20, 2024
Project endJuly 31, 2025
Funding year2024
Award (this year)$485,026
NIH project number1R43NS135863-01A1
Project IDNIH-11006736 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults over 21 years old who experience chronic pain in the arm and neck, particularly those who have not found relief from traditional treatments.

Less likely to help

Patients with acute pain conditions or those who do not have chronic arm or neck pain may not benefit from this research.

What this research studies

This research investigates a novel type of epidural stimulation lead designed to alleviate chronic arm and neck pain. The approach involves creating thinner and softer leads that can be implanted in the cervical spine, which is currently challenging due to the limitations of existing devices. By using advanced materials that allow the leads to soften and conform to the spinal cord after implantation, the study aims to improve the stability and effectiveness of spinal cord stimulation. The research builds on promising preliminary results from animal studies and aims to translate these findings to human applications.

Why it matters

Potential benefit: If successful, this research could provide a new, effective treatment option for patients suffering from chronic arm and neck pain.

How similar studies have gone: Other research has shown success with similar approaches in spinal cord stimulation, but this specific application with softening leads is novel.

Where this research is happening

  • Backstop Neural, INC.
    Dallas, United States
    Active

Researchers

  • Principal investigator: Manz, Connie — Backstop Neural, INC.
  • Study coordinator: Manz, Connie

Related research

Other NIH-funded projects on the same topics.

  • Identifying new targets to treat chronic neck pain from the C1-2 joint

    Researchers are studying tissue from people with neck pain to find molecular clues that could lead to better, non-opioid treatments.

    NIH research University of Washington · Seattle, United States · NIH-11363674

  • New molecular targets for chronic C1–C2 (atlanto‑axial) neck pain

    Using tissue removed during neck surgery to look for molecular signals that could lead to better treatments for people with chronic neck pain from the atlanto‑axial joint.

    NIH research University of Washington · Seattle, United States · NIH-11173593

  • Combining chiropractic care and Tai Chi to help older adults with neck pain

    This study is looking at how well combining chiropractic care with Tai Chi can help older adults with chronic neck pain feel better and improve their overall well-being, while also gathering feedback from participants about their experiences.

    NIH research Brigham and Women's Hospital · Boston, United States · NIH-11045394

  • A smart patch for managing neck pain

    This study is testing a new wireless patch with tiny needles that can help relieve neck pain without the side effects of pills, making it a friendly option for people looking for better pain management.

    NIH research University of Virginia · Charlottesville, United States · NIH-10952422

  • Finding new treatment targets for chronic neck pain using RNA sequencing.

    This study is looking at the causes of chronic neck pain, especially related to arthritis in a specific joint, by analyzing tissue samples from patients having surgery, to find out what makes the pain different from those with short-term pain, which could help in developing better treatments.

    NIH research University of Washington · Seattle, United States · NIH-10912656

  • Combining chiropractic care and Tai Chi to help with chronic neck pain

    This study is looking at how well chiropractic care and Tai Chi work together to help people with chronic neck pain feel better and improve their quality of life.

    NIH research Brigham and Women's Hospital · Boston, United States · NIH-10866430

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.