New ECG algorithm to detect dangerous heart rhythms in hospitalized patients
Official title: Evaluation of a novel ECG algorithm to identify and predict ventricular tachycardia in ICU and non-ICU patients with in-hospital cardiac arrest
Funded at University of California, San Francisco · NIH-11013335 · Data updated 2026-11-12
This study is working on a new way to better spot a dangerous heart rhythm called ventricular tachycardia in patients who have heart emergencies in the hospital, so doctors can respond quickly and accurately without being distracted by false alarms.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | February 1, 2024 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $725,331 |
| NIH project number | 5R01HL167975-02 |
| Project ID | NIH-11013335 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults over 21 years old who are hospitalized and at risk of experiencing cardiac arrest due to abnormal heart structures or arrhythmias.
✕Less likely to help
Patients who are not hospitalized or those with stable heart conditions that do not require continuous ECG monitoring may not benefit from this research.
What this research studies
This research focuses on improving the detection of ventricular tachycardia (VT), a critical heart rhythm that can lead to cardiac arrest, in patients who experience in-hospital cardiac arrests. The study aims to develop a novel electrocardiogram (ECG) algorithm that reduces false alarms, which can hinder timely treatment. By analyzing existing ECG data and refining the algorithm, the research seeks to enhance the accuracy of VT identification, ensuring that healthcare providers can respond more effectively during emergencies. Patients will be monitored using advanced ECG technology to assess the algorithm's performance in real-time clinical settings.
Why it matters
Potential benefit: If successful, this research could significantly improve survival rates and neurological outcomes for patients experiencing cardiac arrest by ensuring quicker and more accurate identification of life-threatening heart rhythms.
How similar studies have gone: Previous research has indicated that improving ECG algorithms can lead to better identification of arrhythmias, suggesting that this approach has potential for success.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Pelter, Michele M. — University of California, San Francisco
- Study coordinator: Pelter, Michele M.
Related research
Other NIH-funded projects on the same topics.
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AI-powered ECG tool to quickly detect and predict ventricular tachycardia during in-hospital cardiac arrest
A new AI-enhanced ECG algorithm is being developed to rapidly identify and forecast dangerous ventricular rhythms in adults with in-hospital cardiac arrest, aiming to improve defibrillation timing.
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Map heart tissue to guide VT ablation with AI help
A patient-oriented project aims to use AI-based mapping to better identify abnormal heart tissue responsible for ventricular tachycardia and guide safer, faster ablation.
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Proton SBRT for refractory ventricular tachycardia with real-time 3D/4D imaging
A patient-facing study exploring a proton-based, noninvasive radiation therapy to treat stubborn VT using advanced 3D and 4D imaging to target the heart safely.
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Venous ethanol ablation to treat ischemic VT (VE-VT)
A new treatment approach uses ethanol delivered through heart veins to help stop dangerous heart rhythms in patients with previous heart damage.
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Novel gene therapy tools to prevent dangerous heart rhythms
A small grant supports testing gene-therapy methods to stop ventricular tachycardia after a heart attack, with the goal of helping people at risk of sudden heart rhythm problems.
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Radiation-guided ablation for ventricular tachycardia
This project tests a noninvasive radiation approach to ablate heart tissue in people with dangerous ventricular tachycardia to reduce the need for invasive procedures.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.