New devices for heart valve repair using advanced techniques
SBIR TOPIC 112, FAST-TRACK, INTRAMYOCARDIAL SUTURE ANNULOPLASTY SYSTEM ("MIRTH" AND "SCIMITAR" DEVICES)
This study is testing new tools that can help fix heart valves without major surgery, making it easier and safer for patients to recover.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Transmural Systems, LLC NIH-funded |
| Lab location | 1 site (Andover, United States) |
| Project ID | NIH-10819110 on NIH RePORTER |
What this research studies
This research focuses on developing innovative devices, known as MIRTH and SCIMITAR, to repair heart valves through minimally invasive procedures. By navigating through the heart's veins, these devices aim to perform annuloplasty, which is the surgical repair of heart valves, without the need for open-heart surgery. The approach is designed to improve patient outcomes by reducing recovery time and minimizing surgical risks. Clinical evaluations will assess the effectiveness and safety of these new devices in real-world settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with mitral or tricuspid valve issues who are seeking less invasive treatment options.
Not a fit: Patients with severe heart conditions that require traditional open-heart surgery may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective heart valve repair options for patients.
How similar studies have performed: Similar innovative approaches in minimally invasive cardiac procedures have shown promise, suggesting potential success for these new devices.
Where this research is happening
Andover, United States
- Transmural Systems, LLC — Andover, United States (Active)
Researchers
- Principal investigator: Rafiee, Nasser — Transmural Systems, LLC
- Study coordinator: Rafiee, Nasser
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.