New criteria and tools for diagnosing pediatric sepsis

Novel Pediatric Sepsis Criteria and Clinical Decision Support Tools

['FUNDING_R01'] · UNIVERSITY OF COLORADO DENVER · NIH-10904921

This study is working on new ways to help doctors spot sepsis in children more quickly and accurately, so they can get the right care sooner.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF COLORADO DENVER (nih funded)
Locations1 site (Aurora, UNITED STATES)
Trial IDNIH-10904921 on ClinicalTrials.gov

What this research studies

This research aims to develop and validate new criteria for diagnosing pediatric sepsis, which is a critical condition affecting children. The current diagnostic criteria are outdated and do not effectively identify sepsis early, especially in various healthcare settings. By focusing on organ dysfunction as a key indicator, the research seeks to create a more accurate and applicable framework for diagnosing sepsis in children. This approach will involve analyzing clinical data to determine the best measures for identifying sepsis in pediatric patients.

Who could benefit from this research

Good fit: Ideal candidates for this research include children aged 0-11 years who are at risk for or suspected of having sepsis.

Not a fit: Patients who are older than 11 years or those who do not present with signs of infection may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of pediatric sepsis, potentially saving lives and improving outcomes for critically ill children.

How similar studies have performed: Previous research has shown success in redefining sepsis criteria for adults, suggesting that a similar approach for pediatric patients could also be effective.

Where this research is happening

Aurora, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.