New contrast agents for better breast cancer screening

Silver Telluride Nanoparticle Dual-Energy Mammography Contrast Agents For Breast Cancer Screening

NIH-funded research University of Pennsylvania · NIH-11129126

This study is looking at a new way to help women with dense breasts get better breast cancer screenings by using special tiny particles that could make the tests safer and more effective than the current methods.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-11129126 on NIH RePORTER

What this research studies

This research focuses on improving breast cancer screening for women with dense breasts, who are at a higher risk for the disease. It investigates the use of silver telluride nanoparticles as contrast agents in dual-energy mammography, a technique that enhances the detection of breast cancer. The study aims to address the limitations of current iodine-based contrast agents, which can cause allergic reactions and have a narrow imaging window. By developing these novel nanoparticles, the research seeks to provide a more effective and safer screening option for at-risk women.

Who could benefit from this research

Good fit: Ideal candidates for this research are women with dense breast tissue who are at an increased risk for breast cancer.

Not a fit: Patients with non-dense breast tissue may not receive significant benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and safer breast cancer screenings for women with dense breasts.

How similar studies have performed: Previous research has shown promise in using novel contrast agents for imaging, suggesting potential success for this approach.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.