New contrast agent for safer heart imaging
Manganese-based Contrast Agent for Cardiovascular MRI
This study is testing a new, safer contrast agent made from manganese for heart MRI scans, designed especially for people with kidney problems, to help doctors get clearer images of the heart without the usual risks.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Reveal Pharma NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project ID | NIH-10846650 on NIH RePORTER |
What this research studies
This research focuses on developing a manganese-based contrast agent for cardiovascular MRI, aiming to improve the safety and effectiveness of heart imaging. The study addresses the risks associated with current contrast agents, particularly for patients with kidney issues, by providing a non-toxic alternative that enhances imaging quality without the harmful side effects. By utilizing advanced imaging techniques, the research seeks to offer better diagnostic capabilities for heart disease, which is a leading cause of death globally.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults with cardiovascular diseases who may also have renal impairment.
Not a fit: Patients without cardiovascular issues or those who do not have any risk factors for kidney problems may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more accurate heart imaging for patients, particularly those with kidney problems.
How similar studies have performed: Previous research has shown promise in developing safer imaging agents, but this manganese-based approach is relatively novel and untested.
Where this research is happening
Cambridge, United States
- Reveal Pharma — Cambridge, United States (Active)
Researchers
- Principal investigator: Hoffman, Vera — Reveal Pharma
- Study coordinator: Hoffman, Vera
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.