New contraceptive device using smart polymer fibers

SMART Polymer Fibers For Tampon-Like Nonsteroidal Contraceptive Devices

NIH-funded research St. Louis College of Pharmacy · NIH-10689053

This study is exploring a new type of birth control that uses special materials to create a safe environment in the vagina that makes it hard for sperm to move, offering a hormone-free option for people looking for on-demand contraception.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionSt. Louis College of Pharmacy NIH-funded
Lab location1 site (St. Louis, UNITED STATES)
Project IDNIH-10689053 on NIH RePORTER

What this research studies

This research investigates a novel contraceptive method that utilizes smart polymer fibers designed to create an inhospitable environment for sperm upon exposure to seminal fluid. The approach involves developing mucoadhesive, bioresponsive materials that maintain a physiologically acidic pH, which is crucial for reducing sperm motility. By transforming the vaginal cavity into a protective environment, this method aims to provide on-demand contraception without the use of hormones. The research is focused on advancing this innovative technology towards human testing more efficiently than traditional methods.

Who could benefit from this research

Good fit: Ideal candidates for this research are women seeking non-hormonal contraceptive methods.

Not a fit: Patients who are not seeking contraception or those who have contraindications to vaginal devices may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide women with a new, non-hormonal contraceptive option that is easy to use and effective.

How similar studies have performed: While the concept of using bioresponsive materials for contraception is innovative, similar approaches in the field of non-drug contraceptives have shown promise, indicating potential for success.

Where this research is happening

St. Louis, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.