NIH-funded research R01 grant

New contact lenses for delivering drugs to the back of the eye

Official title: Back of the eye drug delivery: Novel contact lenses, pathways, and in-silico modeling

Funded at Colorado School of Mines · NIH-11042863 · Data updated 2026-11-12

This study is working on new contact lenses that can deliver medicine right to the back of your eye, making it easier and safer to treat conditions like age-related macular degeneration without the need for painful injections.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionColorado School of Mines
NIH-funded
Lab location1 site (Golden, United States)
Project startSeptember 30, 2023
Project endJanuary 31, 2027
Funding year2025
Award (this year)$468,554
NIH project number5R01EY034477-03
Project IDNIH-11042863 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals suffering from age-related macular degeneration or other retinal diseases who require ongoing treatment.

Less likely to help

Patients with conditions that do not affect the back of the eye or those who are not suitable for contact lens use may not benefit from this research.

What this research studies

This research focuses on developing innovative contact lenses that can deliver medications directly to the back of the eye, which is crucial for treating retinal diseases. Traditional treatments often require invasive injections that can lead to complications, while topical eye drops are ineffective due to low drug absorption. The study aims to enhance drug delivery through contact lenses by exploring the mechanisms involved and creating predictive models for their effectiveness. By improving the way drugs are administered, this research seeks to provide a safer and more effective treatment option for patients with age-related macular degeneration and other retinal conditions.

Why it matters

Potential benefit: If successful, this research could significantly reduce the need for invasive injections and improve treatment outcomes for patients with retinal diseases.

How similar studies have gone: While there has been some success in using contact lenses for anterior segment diseases, the approach for back of the eye delivery is relatively novel and has not been extensively tested.

Where this research is happening

  • Colorado School of Mines
    Golden, United States
    Active

Researchers

  • Principal investigator: Chauhan, Anuj — Colorado School of Mines
  • Study coordinator: Chauhan, Anuj

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.