New contact lenses for delivering drugs to the back of the eye

Back of the eye drug delivery: Novel contact lenses, pathways, and in-silico modeling

NIH-funded research Colorado School of Mines · NIH-11042863

This study is working on new contact lenses that can deliver medicine right to the back of your eye, making it easier and safer to treat conditions like age-related macular degeneration without the need for painful injections.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionColorado School of Mines NIH-funded
Lab location1 site (Golden, United States)
Project IDNIH-11042863 on NIH RePORTER

What this research studies

This research focuses on developing innovative contact lenses that can deliver medications directly to the back of the eye, which is crucial for treating retinal diseases. Traditional treatments often require invasive injections that can lead to complications, while topical eye drops are ineffective due to low drug absorption. The study aims to enhance drug delivery through contact lenses by exploring the mechanisms involved and creating predictive models for their effectiveness. By improving the way drugs are administered, this research seeks to provide a safer and more effective treatment option for patients with age-related macular degeneration and other retinal conditions.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from age-related macular degeneration or other retinal diseases who require ongoing treatment.

Not a fit: Patients with conditions that do not affect the back of the eye or those who are not suitable for contact lens use may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the need for invasive injections and improve treatment outcomes for patients with retinal diseases.

How similar studies have performed: While there has been some success in using contact lenses for anterior segment diseases, the approach for back of the eye delivery is relatively novel and has not been extensively tested.

Where this research is happening

Golden, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions age related macular disease
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.