New combination therapies to fight drug-resistant malaria
Novel Synergistic Antimalarials with Resistance Reversal Function
This study is working on new malaria medications that are stronger and safer, helping to fight against drug-resistant parasites, so patients can have better and more affordable treatment options.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Portland VA Medical Center NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-11098524 on NIH RePORTER |
What this research studies
This research focuses on developing innovative antimalarial drugs that can effectively combat the growing issue of drug resistance in malaria-causing parasites. By creating a new type of medication that combines the strengths of existing treatments, the research aims to enhance the effectiveness of antimalarial therapies. The approach involves optimizing a specific chemical compound to improve its potency and ability to work alongside other drugs, ultimately aiming to provide a more sustainable solution for malaria treatment. Patients may benefit from these new therapies that could be safer, more effective, and less expensive than current options.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with malaria, particularly those infected with drug-resistant strains.
Not a fit: Patients who do not have malaria or are not affected by drug-resistant malaria strains may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and sustainable treatments for malaria, significantly improving patient outcomes.
How similar studies have performed: Previous research has shown promise in developing combination therapies for malaria, indicating that this approach could lead to significant advancements in treatment.
Where this research is happening
Portland, United States
- Portland VA Medical Center — Portland, United States (Active)
Researchers
- Principal investigator: Kelly, Jane X — Portland VA Medical Center
- Study coordinator: Kelly, Jane X
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.