New cell therapy for managing pain from chronic pancreatitis

Who could benefit from this research

What this research studies

This research investigates a novel cellular therapy using mesenchymal stromal cells (MSCs) to treat chronic pain associated with chronic pancreatitis. The approach aims to provide an effective pain management solution that avoids the risks associated with opioid medications, which are often ineffective and can lead to addiction. By focusing on the unique pain mechanisms in chronic pancreatitis, the research seeks to develop a treatment that could improve the quality of life for patients suffering from severe abdominal pain. The study will involve harvesting and expanding MSCs for therapeutic use, with the goal of translating these findings into clinical practice for veterans and others affected by chronic pain.

Why it matters

Where this research is happening

• Ralph H Johnson VA Medical Center
  Charleston, United States Active

Researchers

• Principal investigator: Wang, Hongjun — Ralph H Johnson VA Medical Center
• Study coordinator: Wang, Hongjun

Related research

Other NIH-funded projects on the same topics.

• Chronic Pancreatitis and Related Conditions Data Center Supports Multi-Center Research

  A national effort to organize and share clinical data and biosamples from people with chronic pancreatitis, pancreatogenic diabetes, and pancreatic cancer to speed biomarker discovery and new treatments.

  NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-11592146

• Malabsorption Blood Test for Exocrine Pancreatic Function in Chronic Pancreatitis

  A blood test (MBT) will help identify people with mild to moderate pancreatic fat malabsorption and show how well enzyme therapy improves their quality of life.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11415052

• Chronic Pancreatitis Clinical Research Cohort and Biorepository

  A long-term study at UF/Advent Health following adults with acute, relapsing, and chronic pancreatitis to build a detailed group with biospecimens and data for better diagnosis and personalized care.

  NIH research University of Florida · Gainesville, United States · NIH-11408761

• Cedars-Sinai Center leads research on chronic pancreatitis and pancreatic cancer

  A Cedars-Sinai research center is renewing its program to study chronic pancreatitis, diabetes-related pancreatic disease, and pancreatic cancer so doctors can better understand and treat these conditions.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11401819

• UPMC Center for Pancreatitis and Diabetes research program

  A specialized center at the University of Pittsburgh is advancing clinical and biological studies of chronic pancreatitis, recurrent acute pancreatitis, and diabetes to improve understanding and care.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11401437

• Chronic Pancreatitis Research Network to Understand Symptoms and Find Treatments

  This project advances studies of chronic pancreatitis to understand why some people progress and to test new ideas that could diagnose or slow the disease.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11400539

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.