New cell therapy for managing pain from chronic pancreatitis
Novel Cellular Therapy for the treatment of pain associated with chronic pancreatitis
This study is looking at a new treatment using special cells to help manage the severe abdominal pain caused by chronic pancreatitis, aiming to offer a safer option than opioids for veterans and others dealing with this tough condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ralph H Johnson VA Medical Center NIH-funded |
| Lab location | 1 site (Charleston, United States) |
| Project ID | NIH-11044062 on NIH RePORTER |
What this research studies
This research investigates a novel cellular therapy using mesenchymal stromal cells (MSCs) to treat chronic pain associated with chronic pancreatitis. The approach aims to provide an effective pain management solution that avoids the risks associated with opioid medications, which are often ineffective and can lead to addiction. By focusing on the unique pain mechanisms in chronic pancreatitis, the research seeks to develop a treatment that could improve the quality of life for patients suffering from severe abdominal pain. The study will involve harvesting and expanding MSCs for therapeutic use, with the goal of translating these findings into clinical practice for veterans and others affected by chronic pain.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who suffer from chronic pancreatitis and associated abdominal pain.
Not a fit: Patients with chronic pain not related to chronic pancreatitis or those who are not eligible for cellular therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could offer a new, effective treatment option for patients suffering from chronic pain without the risks associated with opioid use.
How similar studies have performed: Other research has shown promise in using cellular therapies for pain management, indicating potential success for this novel approach.
Where this research is happening
Charleston, United States
- Ralph H Johnson VA Medical Center — Charleston, United States (Active)
Researchers
- Principal investigator: Wang, Hongjun — Ralph H Johnson VA Medical Center
- Study coordinator: Wang, Hongjun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.