New cell culture platform for developing prostate cancer treatments
Official title: Evaluation of novel microscale cell culture platform for translational drug development in prostate cancer
Funded at Wm S. Middleton Memorial Veterans Hosp · NIH-10928083 · Data updated 2026-11-12
This study is working to find better treatments for prostate cancer, especially for Veterans, by growing tumor models from their own cells to see how well new therapies might work for them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wm S. Middleton Memorial Veterans Hosp NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| NIH project number | 5I01CX002479-02 |
| Project ID | NIH-10928083 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are Veterans diagnosed with prostate cancer.
✕Less likely to help
Patients with prostate cancer who are not Veterans may not receive direct benefits from this research.
What this research studies
This research focuses on improving the development of effective treatments for prostate cancer, particularly in Veterans who are disproportionately affected by this disease. The team has created a novel microfluidic cell culture platform that allows for the growth of tumor models using cells derived from patients. By using these patient-derived cells, the research aims to better mimic the tumor environment and improve the prediction of how well potential therapies will work in real patients. The study will involve testing the gene expression profiles of these models to see how closely they align with actual patient profiles.
Why it matters
Potential benefit: If successful, this research could lead to more effective prostate cancer treatments tailored specifically for Veterans.
How similar studies have gone: While there have been advancements in cancer treatment development, this specific approach using a novel microfluidic platform is relatively new and has not been extensively tested.
Where this research is happening
-
Wm S. Middleton Memorial Veterans Hosp
Madison, United States Active
Researchers
- Principal investigator: Kosoff, David — Wm S. Middleton Memorial Veterans Hosp
- Study coordinator: Kosoff, David
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.