New catheters that release Nitric Oxide to prevent infections and blood clots
Ultra-low Fouling and Anti-infective and Anti-thrombotic Nitric Oxide Releasing Intravascular Catheters
This study is testing new catheters that release a natural substance called Nitric Oxide to help prevent infections and blood clots, making them safer and more effective for patients who need them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Nytricx INC. NIH-funded |
| Lab location | 1 site (Athens, United States) |
| Project ID | NIH-11139086 on NIH RePORTER |
What this research studies
This research focuses on developing innovative intravascular catheters that release Nitric Oxide (NO), a natural substance that helps prevent infections and blood clots. The catheters are designed with a special polymer matrix that mimics the body's natural release of NO, targeting both the internal and external surfaces of the catheter. By doing so, the technology aims to reduce the risk of chronic infections and thrombosis, which are common complications associated with traditional catheters. Patients using these catheters may experience fewer complications and longer-lasting devices, improving their overall treatment experience.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who require long-term catheterization for medical treatments.
Not a fit: Patients who do not require catheterization or have contraindications for catheter use may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of infections and blood clots in patients requiring intravascular catheters.
How similar studies have performed: Similar approaches using NO-releasing technologies have shown promise in other medical applications, indicating potential for success in this novel catheter design.
Where this research is happening
Athens, United States
- Nytricx INC. — Athens, United States (Active)
Researchers
- Principal investigator: Shebuski, Ronald J. — Nytricx INC.
- Study coordinator: Shebuski, Ronald J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.