New cannabinoids for treating cancer pain without addiction

Peripherally-restricted non-addictive cannabinoids for cancer pain treatment

NIH-funded research University of California Los Angeles · NIH-10726405

This study is working on new pain relief options for cancer patients that won't cause addiction like regular painkillers, aiming to help manage pain safely without affecting the brain.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-10726405 on NIH RePORTER

What this research studies

This research focuses on developing new synthetic cannabinoids that specifically target pain relief for cancer patients without the addictive side effects associated with traditional opioids. The approach involves creating compounds that do not cross the blood-brain barrier, thereby minimizing central nervous system side effects while effectively managing chronic pain. The research includes a series of laboratory tests and studies to ensure these new treatments are both safe and effective for patients suffering from cancer-related pain.

Who could benefit from this research

Good fit: Ideal candidates for this research are cancer patients experiencing chronic pain who are seeking alternative pain management solutions.

Not a fit: Patients who do not have cancer or are not experiencing chronic pain may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a safer and more effective pain management option for cancer patients, reducing reliance on opioids.

How similar studies have performed: Previous research has shown promise in using cannabinoids for pain management, but this specific approach with peripherally-restricted cannabinoids is novel.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.