New biosensors to detect how cells respond to their environment
A new class of biosensors for detecting signaling dynamics without live-cell microscopy
['FUNDING_R01'] · PRINCETON UNIVERSITY · NIH-10906320
This study is working on new tools that can track how cells react to their environment without needing to look at them under a microscope, which could help us learn more about important processes like how embryos develop, how tissues heal, and how cancer grows.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PRINCETON UNIVERSITY (nih funded) |
| Locations | 1 site (Princeton, UNITED STATES) |
| Trial ID | NIH-10906320 on ClinicalTrials.gov |
What this research studies
This research focuses on developing innovative biosensors that can monitor the dynamic signaling processes within cells without the need for live-cell microscopy. By understanding how cells sense and respond to their surroundings, particularly through growth factor signaling, the research aims to uncover the intricate patterns of protein activity that dictate cellular behavior. This could lead to advancements in our understanding of critical processes such as embryo development, tissue regeneration, and cancer progression. The biosensors will allow for real-time tracking of cellular responses, providing valuable insights into cell communication and signaling.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals affected by conditions related to cell signaling, such as cancer patients or those undergoing tissue regeneration therapies.
Not a fit: Patients with conditions unrelated to cell signaling dynamics may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of cellular processes, leading to improved treatments for conditions like cancer and better strategies for tissue regeneration.
How similar studies have performed: Other research has successfully utilized biosensors to study cellular signaling, indicating a promising approach in this field.
Where this research is happening
Princeton, UNITED STATES
- PRINCETON UNIVERSITY — Princeton, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TOETTCHER, JARED E — PRINCETON UNIVERSITY
- Study coordinator: TOETTCHER, JARED E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers