New biomarkers for early detection of liver cancer spread
AND-gated Synthetic Biomarkers for Early Detection of Liver Metastasis
This study is working on a new way to spot early signs of liver cancer spreading in patients by using special sensors that can detect specific signals in your urine and blood, helping doctors keep a closer eye on your health.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgia Institute of Technology NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10915466 on NIH RePORTER |
What this research studies
This research focuses on developing innovative synthetic biomarkers that can detect early signs of liver metastasis in cancer patients. By utilizing engineered biological sensors, the project aims to create a system that can identify specific tumor-related signals in bodily fluids like urine and serum. These biomarkers are designed to be administered throughout the body, allowing for real-time monitoring of cancer progression and improving the accuracy of early detection. The approach leverages advanced synthetic biology techniques to enhance the specificity and safety of cancer diagnostics.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at high risk for liver cancer or those with existing cancers that may spread to the liver.
Not a fit: Patients with no history of cancer or those whose cancer is already at an advanced stage may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate detection of liver metastasis, potentially improving treatment outcomes for patients.
How similar studies have performed: Other research has shown promise in using synthetic biology for cancer diagnostics, indicating that this approach could be a significant advancement in the field.
Where this research is happening
Atlanta, United States
- Georgia Institute of Technology — Atlanta, United States (Active)
Researchers
- Principal investigator: Kwong, Gabriel a — Georgia Institute of Technology
- Study coordinator: Kwong, Gabriel a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.