New advanced EPR spectrometer for biological research
Official title: Bruker ELEXSYS-II E500 X-band CW EPR spectrometer system
Funded at Medical College of Wisconsin · NIH-10852355 · Data updated 2026-11-12
This study is about getting a new, advanced machine that helps scientists better understand how proteins and enzymes work, which could lead to new treatments for patients in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical College of Wisconsin NIH-funded |
| Lab location | 1 site (Milwaukee, United States) |
| Project start | May 1, 2024 |
| Project end | April 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $471,670 |
| NIH project number | 1S10OD036246-01 |
| Project ID | NIH-10852355 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals with conditions related to enzyme dysfunction or oxidative stress.
✕Less likely to help
Patients with conditions unrelated to the biological processes studied using EPR spectroscopy may not receive direct benefits.
What this research studies
This research involves acquiring a state-of-the-art Bruker ELEXSYS-II E500 X-band continuous wave electron paramagnetic resonance (EPR) spectrometer system to replace an outdated instrument. The new system offers significantly improved sensitivity and reliability, which will enhance various research projects related to structural biology, enzyme reactions, and drug discovery. Patients may benefit indirectly through advancements in understanding biological processes and developing new treatments based on the findings from this enhanced research capability.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding diseases and developing new therapies.
How similar studies have gone: Other research utilizing advanced EPR spectroscopy has shown promising results in understanding complex biological systems, indicating a strong potential for success with this new instrument.
Where this research is happening
-
Medical College of Wisconsin
Milwaukee, United States Active
Researchers
- Principal investigator: Klug, Candice S — Medical College of Wisconsin
- Study coordinator: Klug, Candice S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.