Neuropathology core supports brain tissue research for Alzheimer’s and related dementias
Official title: Neuropathology Core
Funded at Northern California Institute/res/edu · NIH-11395229 · Data updated 2026-11-12
A dedicated program collects and analyzes brain tissue from study participants to help doctors understand Alzheimer’s and similar dementias, and to improve biomarkers used in diagnosis and trials.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northern California Institute/res/edu NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | September 30, 2004 |
| Project end | July 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $718,128 |
| NIH project number | 5U19AG024904-19 |
| Project ID | NIH-11395229 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with Alzheimer’s disease or related dementias who contribute brain tissue or participate in related biomarker studies through the ADNI network.
✕Less likely to help
Patients not involved in brain donation or biomarker studies may not directly benefit from this core.
What this research studies
If you or a loved one is affected by Alzheimer’s or a related dementia, this grant helps ensure brain tissue from participants is collected and examined in a standardized way. Researchers compare clinic diagnoses, fluid biomarkers, and brain imaging to the gold-standard findings from neuropathology. The work supports identifying and validating biomarkers that reflect brain changes, which could lead to better diagnosis and monitoring in the future. The Neuropathology Core also organizes and stores brain tissue to support current and future biomarker studies and clinical trials.
Why it matters
Potential benefit: Improved accuracy of biomarker-based diagnosis and better understanding of disease progression for ADRD.
How similar studies have gone: Previous work in ADNI has established standardized brain examinations and tissue banking that support biomarker research and trial design.
Where this research is happening
-
Northern California Institute/res/edu
San Francisco, United States Active
Researchers
- Principal investigator: Perrin, Richard Justin — Northern California Institute/res/edu
- Study coordinator: Perrin, Richard Justin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.