NIH-funded research R01 grant

Neural basis of how kids and animals respond to new tastes

Official title: The Neural Organization of Taste Neophobia

Funded at University of Tennessee Health Sci Ctr · NIH-11365145 · Data updated 2026-11-12

This grant studies how the brain handles fear of new foods and how that affects eating in children, using animal models to understand the brain circuits involved.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Tennessee Health Sci Ctr
NIH-funded
Lab location1 site (Memphis, United States)
Project startAugust 2, 2022
Project endJuly 31, 2027
Funding year2026
Award (this year)$385,000
NIH project number5R01DC020465-05
Project IDNIH-11365145 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are children with high food neophobia or caregivers seeking ways to support diverse, healthy eating.

Less likely to help

Children without neophobia or those not involved in appetite-related studies may see limited direct benefit.

What this research studies

The project explores why children and other animals are cautious when tasting unfamiliar foods and how this early flavor experience shapes future eating. Researchers will examine brain regions involved in taste and neophobia in awake, behaving animals to map neural responses to novel tastes. Insights could illuminate why some kids develop picky eating or unhealthy dietary patterns and how to support healthier food choices.

Why it matters

Potential benefit: Understanding these brain circuits could lead to strategies that reduce unhealthy food avoidance in children and promote better dietary habits.

How similar studies have gone: Prior work shows taste neophobia involves specific brain circuits; this study aims to extend findings to awake, behaving animals.

Where this research is happening

  • University of Tennessee Health Sci Ctr
    Memphis, United States
    Active

Researchers

  • Principal investigator: Boughter, John D — University of Tennessee Health Sci Ctr
  • Study coordinator: Boughter, John D

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.