Network for improving care in critically ill children

Collaborative Pediatric Critical Care Research Network

['FUNDING_OTHER'] · UNIVERSITY OF UTAH · NIH-10915491

This study is looking to improve treatments for critically ill children with sepsis-related organ issues by testing personalized therapies that match their unique immune systems, and it’s designed for kids who are facing these serious health challenges.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF UTAH (nih funded)
Locations1 site (SALT LAKE CITY, UNITED STATES)
Trial IDNIH-10915491 on ClinicalTrials.gov

What this research studies

This research focuses on enhancing the treatment of critically ill children by establishing a collaborative network that conducts large-scale clinical trials and observational studies. The project aims to investigate personalized immune modulation therapies for children suffering from sepsis-induced multiple organ dysfunction syndrome (MODS). By utilizing a diverse network of clinical sites, the research will explore how tailored treatments can improve patient outcomes. The study will involve randomized controlled trials that assess the effectiveness of specific immunomodulatory treatments based on individual immune profiles.

Who could benefit from this research

Good fit: Ideal candidates for this research are critically ill children aged 0-21 years who are experiencing sepsis-induced multiple organ dysfunction syndrome.

Not a fit: Patients who are not critically ill or do not have sepsis-induced multiple organ dysfunction syndrome may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved survival rates and recovery outcomes for critically ill children with sepsis.

How similar studies have performed: Previous studies within the CPCCRN have shown promising results in understanding immune responses in critically ill children, indicating a strong foundation for this innovative approach.

Where this research is happening

SALT LAKE CITY, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.