NIH-funded research R01 grant

Neighborhood factors and ADRD progression across communities

Official title: Longitudinal Neighborhood Determinants of ADRD Progression within a Multi-Site Cohort

Funded at Drexel University · NIH-11449912 · Data updated 2026-11-12

This project studies how where you live affects the progression of Alzheimer's disease and related dementias over time.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDrexel University
NIH-funded
Lab location1 site (Philadelphia, United States)
Project startMay 15, 2021
Project endJune 30, 2031
Funding year2026
Award (this year)$1,171,730
NIH project number2R01AG072634-06A1
Project IDNIH-11449912 on NIH RePORTER

Who could benefit from this research

Could help

Individuals at risk for ADRD or living with ADRD who are part of the studied cohorts or similar community-dwelling populations.

Less likely to help

People not represented in the study populations or outside the studied neighborhoods may not directly benefit.

What this research studies

From a patient perspective, this grant uses long-term data from diverse neighborhoods to understand how living environments influence cognitive decline in ADRD. It builds on a large, multi-site cohort with detailed neighborhood information and cognitive assessments to identify when and how neighborhood factors matter most. The study aims to reveal modifiable community factors that could help people maintain cognition for longer and slow disease progression. Findings could guide community-level interventions and policies that support aging individuals with ADRD.

Why it matters

Potential benefit: If successful, the work could inform community and policy changes that help people with ADRD maintain independence and cognitive health longer.

How similar studies have gone: Prior work has shown links between neighborhood conditions and cognitive outcomes, supporting the potential for meaningful findings in this area.

Where this research is happening

  • Drexel University
    Philadelphia, United States
    Active

Researchers

  • Principal investigator: Hirsch, Jana Ariel — Drexel University
  • Study coordinator: Hirsch, Jana Ariel

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Browse more
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.