Neighborhood conditions during pregnancy and mothers' future heart and lung health
The impact of neighborhood factors during pregnancy on future cardiopulmonary health
This project looks at whether neighborhood conditions during pregnancy are linked to heart and lung health in birthing people three and five years after delivery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11145764 on NIH RePORTER |
What this research studies
You would join a follow-up of 440 people from the Generation C pregnancy cohort who were recruited in New York City in 2020–2022. The team will combine neighborhood-level information (like housing, pollution, and local resources) with medical measures such as blood pressure, lung function tests, and hemoglobin A1c collected at 3 and 5 years after delivery. Researchers will also use blood samples collected during pregnancy to measure inflammation and link those markers to later cardiopulmonary outcomes. Interviews and questionnaires about stress and resilience will help explain how neighborhood exposures and inflammation together influence health over time.
Who could benefit from this research
Good fit: Ideal candidates are people who were part of the Generation C pregnancy cohort in New York City (recruited 2020–2022) and can attend follow-up visits at 3 and 5 years postpartum.
Not a fit: People who were not pregnant during the Generation C recruitment window or who cannot attend follow-up visits or provide medical measurements are unlikely to benefit directly from participation.
Why it matters
Potential benefit: If successful, this work could point to neighborhood-related risks during pregnancy that, when addressed, may reduce future heart and lung disease in mothers.
How similar studies have performed: Prior cohort studies have linked neighborhood factors to preterm birth and to later cardiovascular risk, but combining neighborhood measures, pregnancy inflammation, and long-term cardiopulmonary testing is relatively novel.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Lee, Alison G — Icahn School of Medicine at Mount Sinai
- Study coordinator: Lee, Alison G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.