National teamwork to improve care for chronic lymphocytic leukemia and B‑cell lymphomas
Curing Through Collaboration: Utilizing Cooperative Groups in the Fight Against Chronic Lymphocytic Leukemia and B-cell Lymphomas
['FUNDING_OTHER'] · UNIV OF NORTH CAROLINA CHAPEL HILL · NIH-11294169
This effort brings together national cancer groups to test new targeted and combination treatments for adults with chronic lymphocytic leukemia (CLL) and other B‑cell lymphomas.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIV OF NORTH CAROLINA CHAPEL HILL (nih funded) |
| Locations | 1 site (CHAPEL HILL, UNITED STATES) |
| Trial ID | NIH-11294169 on ClinicalTrials.gov |
What this research studies
I would hear that doctors at UNC and partner cancer centers are running clinical trials of newer targeted drugs and drug combinations for CLL and related B‑cell lymphomas. The project supports a lead clinician who is the international principal investigator on an EVOLVE CLL trial and helps organize SWOG trials so more patients can join. Trials include NCI-sponsored, investigator-initiated, and industry-sponsored options offered at participating cancer centers. The goal is to find better, more effective treatment options and to bring successful approaches into routine care.
Who could benefit from this research
Good fit: Adults diagnosed with chronic lymphocytic leukemia or other B‑cell lymphomas who meet individual trial eligibility criteria would be the intended participants.
Not a fit: People without CLL or B‑cell lymphoma, those under the adult age range, or patients who do not meet specific trial eligibility (for example due to other health conditions) would not benefit directly from these trials.
Why it matters
Potential benefit: If successful, this work could expand treatment choices and improve outcomes for people living with CLL and other B‑cell lymphomas.
How similar studies have performed: Previous trials of targeted agents and combination regimens in CLL and B‑cell lymphomas have already improved care, and this program builds on that progress.
Where this research is happening
CHAPEL HILL, UNITED STATES
- UNIV OF NORTH CAROLINA CHAPEL HILL — CHAPEL HILL, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: STEPHENS, DEBORAH — UNIV OF NORTH CAROLINA CHAPEL HILL
- Study coordinator: STEPHENS, DEBORAH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancer Center