National Fecal Microbiota Transplant (FMT) Registry
Fecal Microbiota Transplant National Registry
This registry collects health and safety information from people who receive fecal microbiota transplants or related live-microbe treatments to help patients with recurrent or severe C. difficile infection.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | American Gastroenterological Assn/inst NIH-funded |
| Lab location | 1 site (Bethesda, United States) |
| Project ID | NIH-11394403 on NIH RePORTER |
What this research studies
You can join if you've had or are planning to have an FMT or a live biotherapeutic product; sites across North America enroll participants. The registry collects medical history, treatment details, and follow-up information using medical record review, regular questionnaires, and sometimes stool or other samples. Researchers track short-term outcomes like infections and procedure results as well as long-term health effects that might appear years later. The goal is to identify rare risks, improve donor and product screening, and guide safer care for people with C. difficile.
Who could benefit from this research
Good fit: Ideal participants are people treated with or planning to receive fecal microbiota transplant or live biotherapeutic products, especially those with recurrent, severe, or fulminant C. difficile infection.
Not a fit: People without C. difficile infection or who are not receiving FMT or related microbiome therapies are unlikely to gain direct benefit from this registry.
Why it matters
Potential benefit: If successful, the registry could make FMT and similar therapies safer and more effective by identifying rare infections, long-term effects, and best practices for screening and treatment.
How similar studies have performed: FMT is already effective for treating recurrent C. difficile infection, but recent reports of transmitted multidrug-resistant organisms and other pathogens mean ongoing registry data are needed to understand and prevent rare harms.
Where this research is happening
Bethesda, United States
- American Gastroenterological Assn/inst — Bethesda, United States (Active)
Researchers
- Principal investigator: Wu, Gary D. — American Gastroenterological Assn/inst
- Study coordinator: Wu, Gary D.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.