NASH Clinical Research Network at Saint Louis University (pediatric and adult components)
Official title: The Saint Louis University Component of the NASH Clinical Research Network
Funded at Saint Louis University · NIH-11365917 · Data updated 2026-11-12
A national program led by Saint Louis University tests treatments and studies for metabolic liver disease affecting adults and children.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Saint Louis University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | May 20, 2002 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $250,000 |
| NIH project number | 5U01DK061718-25 |
| Project ID | NIH-11365917 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults and children with MASLD/MASH who are eligible for clinical trials or translational studies within the NASH CRN network.
✕Less likely to help
People not meeting trial criteria or without MASLD/MASH may not directly benefit from this specific grant activities.
What this research studies
This grant supports the NASH Clinical Research Network’s clinical center at Saint Louis University and its pediatric component at Baylor University, focusing on metabolic dysfunction–associated steatotic liver disease and its most severe form, MASH/NASH. It aims to run clinical trials for therapies and conduct translational research to understand disease mechanisms and improve diagnosis, prevention, and care. The work involves collaboration across sites, patient recruitment, and data collection to advance treatments for both adults and children with MASLD/MASH. Through coordinated clinics and trials, participants may contribute samples, undergo liver-related assessments, and receive standard-of-care monitoring as part of the research framework.
Why it matters
Potential benefit: If successful, the work could lead to better treatments and management strategies for MASLD/MASH, potentially reducing progression to cirrhosis or liver cancer.
How similar studies have gone: The NASH CRN has a history of multi-site trials and translational work with prior renewals and demonstrated progress in MASLD/MASH research.
Where this research is happening
-
Saint Louis University
Saint Louis, United States Active
Researchers
- Principal investigator: Neuschwander-Tetri, Brent a — Saint Louis University
- Study coordinator: Neuschwander-Tetri, Brent a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.