NIH-funded research R01 grant

Multimodal VR framework to support brain rhythms and movement using rhythmic sound and visuals

Official title: Developing a Deep Multimodal Immersive Framework for Cortical Motor Entrainment of Rhythmic Audio-Visual Stimuli

Funded at University of Rhode Island · NIH-11365657 · Data updated 2026-11-12

A new VR-based system uses rhythmic sounds and visuals to help people with motor conditions like stroke or Parkinson’s disease, by studying how the brain links movement with hearing and sight.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Rhode Island
NIH-funded
Lab location1 site (Kingston, United States)
Project startJuly 22, 2026
Project endJune 30, 2029
Funding year2026
Award (this year)$187,400
NIH project number1R01NS144127-01A1
Project IDNIH-11365657 on NIH RePORTER

Who could benefit from this research

Could help

Individuals with stroke or Parkinson’s disease who are exploring rehabilitation options and are able to participate in VR-based tasks.

Less likely to help

Individuals without motor impairment or those unable to engage with VR-based rehabilitation tasks may see limited or no benefit.

What this research studies

This project will create a VR-based, multimodal platform that combines EEG, fNIRS, EMG, and immersive audio-visual stimuli to study how rhythmic cues influence brain networks involved in movement. By analyzing how the motor and auditory areas couple with each other and with muscles during rhythmic entrainment, the team aims to uncover neural mechanisms that support neurorehabilitation. The long-term plan is to translate these insights into targeted, more effective therapies for motor recovery after stroke or Parkinson’s disease. The work will involve developing a VR interface that synchronizes rhythmic auditory stimulation with observed actions to elicit consistent brain and muscle responses. If successful, this framework could guide personalized rehabilitation approaches in clinical settings.

Why it matters

Potential benefit: If successful, the research could lead to better neurorehabilitation strategies for stroke and Parkinson’s disease by leveraging rhythmic audio-visual cues to enhance motor recovery.

How similar studies have gone: Prior studies have shown potential benefits of rhythmic multimodal stimulation for motor tasks, but the specific neural mechanisms and integrative framework are still being explored.

Where this research is happening

  • University of Rhode Island
    Kingston, United States
    Active

Researchers

  • Principal investigator: Shahriari, Yalda — University of Rhode Island
  • Study coordinator: Shahriari, Yalda

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.