NIH-funded research Sbir 2 grant

Multimodal intraoral camera to help detect tooth decay and cracks

Official title: Multimodal intraoral camera

Funded at Light Research, INC. · NIH-11395662 · Data updated 2026-11-12

A compact imaging tool for dental clinics aims to better detect caries and cracked teeth by using four imaging methods in one device.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionLight Research, INC.
NIH-funded
Lab location1 site (Tucson, United States)
Project startSeptember 19, 2024
Project endJuly 31, 2027
Funding year2026
Award (this year)$477,217
NIH project number5R44DE033307-03
Project IDNIH-11395662 on NIH RePORTER

Who could benefit from this research

Could help

Adults and children with suspected dental caries or cracked teeth who visit dental clinics.

Less likely to help

Patients without dental caries or cracks or those not undergoing optical imaging-based assessment may not benefit.

What this research studies

If you have dental caries or a cracked tooth, this project hopes to give clinicians a more precise and earlier diagnosis by combining polarized white light, autofluorescence, optical coherence tomography, and near-infrared transillumination in one small camera. The goal is to provide clearer information about tooth structure so dentists can monitor progress and tailor treatments. The project will develop and move toward commercialization of this multimodal device so clinics can adopt it in everyday care.

Why it matters

Potential benefit: If successful, patients could receive faster, more accurate diagnoses of tooth decay and cracks, leading to earlier and more targeted treatments.

How similar studies have gone: Previous imaging methods alone have limitations; combining modalities is a promising but not yet proven approach for improved diagnosis.

Where this research is happening

  • Light Research, INC.
    Tucson, United States
    Active

Researchers

  • Principal investigator: Wilder-Smith, Petra E — Light Research, INC.
  • Study coordinator: Wilder-Smith, Petra E

Related research

Other NIH-funded projects on the same topics.

  • Compact mouth camera to find cavities and cracked teeth

    A small handheld mouth camera that uses several light-based scans to help dentists spot cavities and cracked teeth earlier in children and adults.

    NIH research Light Research, INC. · Tucson, United States · NIH-11195597

  • Developing a mobile system for early detection and treatment of oral cancer

    This study is working on a mobile system to help find and treat oral cancer early, especially for people in areas with fewer resources, so they can get better care and improve their chances of recovery.

    NIH research Light Research, INC. · Tucson, United States · NIH-11191359

  • A new camera for better detection of dental issues.

    This study is testing a new, small camera that uses different imaging techniques to help dentists find tooth decay and cracks more accurately, so patients can get better diagnoses and personalized treatment plans for their dental health.

    NIH research Light Research, INC. · Tucson, United States · NIH-10760182

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.