Multi-Modal Remote Monitoring for Frontotemporal Degeneration Syndromes
Official title: Phase IIB: A Multi-Modal Remote Monitoring Platform for Frontotemporal Lobar Degeneration Syndromes
Funded at Biosensics, LLC · NIH-11408363 · Data updated 2026-11-12
A small company is testing a wearable and tablet-based system to monitor symptoms in PSP and related disorders in people living with these conditions.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Biosensics, LLC NIH-funded |
| Lab location | 1 site (Newton, UNITED STATES) |
| Project start | September 30, 2022 |
| Project end | May 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $1,000,082 |
| NIH project number | 2R44AG080861-03 |
| Project ID | NIH-11408363 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults diagnosed with PSP or related FTLD syndromes who can participate in wearable monitoring and digital assessments.
✕Less likely to help
Patients unable to wear the device or complete tablet-based assessments may not benefit.
What this research studies
This project uses BioDigit FTLD, a wearable (PAMSys) plus a tablet app to collect objective measurements of daily activity, gait, cognition, speech, and patient-reported data from people with PSP and other FTLD syndromes. The goal is to provide continuous, real-world data that could better reflect how patients feel and function over time. Data from multiple sites, including MGH and Johns Hopkins, has shown usability, reliability, and early clinical validity, with plans to expand to additional FTLD conditions. The platform could streamline future drug development by offering more sensitive and patient-centered outcomes.
Why it matters
Potential benefit: If successful, patients could receive more accurate monitoring of their symptoms and progression, potentially improving clinical care and informing future therapies.
How similar studies have gone: Previous work demonstrated usability and initial validity in PSP with multi-center data; broader validation is ongoing.
Where this research is happening
-
Biosensics, LLC
Newton, United States Active
Researchers
- Principal investigator: Vaziri, Ashkan — Biosensics, LLC
- Study coordinator: Vaziri, Ashkan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.