Multi-channel energy source and catheter system to improve cardiac ablation safety and precision
Official title: Development of a multi-channel radiofrequency and pulsed field energy source generator for cardiac ablation
Funded at Sirona Medical Technologies, INC. · NIH-11540722 · Data updated 2026-11-12
A new energy generator and specialized catheters are being developed to make cardiac ablation safer, more precise, and easier for patients with heart rhythm problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sirona Medical Technologies, INC. NIH-funded |
| Lab location | 1 site (Windsor, United States) |
| Project start | May 15, 2025 |
| Project end | March 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $313,385 |
| NIH project number | 4R33HL173904-02 |
| Project ID | NIH-11540722 on NIH RePORTER |
Who could benefit from this research
✓Could help
People with cardiac arrhythmias who are candidates for catheter ablation and could benefit from safer, more precise energy delivery.
✕Less likely to help
Patients unlikely to benefit are those not considered for ablation or where alternate treatments are already optimal.
What this research studies
This project aims to create a next-generation energy source and multi-electrode catheters that deliver ablation energy more precisely to the targeted heart tissue while reducing energy exposure to surrounding structures. By innovating how energy is delivered and monitored, the team hopes to lower the risk of off-target damage and potentially improve outcomes for people with arrhythmias. The work includes ex-vivo and animal studies to demonstrate lesion size, safety, and procedural practicality before any human testing. If successful, these advances could translate into safer procedures with broader access for patients who need ablation therapy.
Why it matters
Potential benefit: Potentially safer ablation procedures with better precision and accessibility for patients with arrhythmias.
How similar studies have gone: Previous ablation technology improvements have shown promise in improving safety and efficacy, supporting the potential of this approach.
Where this research is happening
-
Sirona Medical Technologies, INC.
Windsor, United States Active
Researchers
- Principal investigator: Haghighi-Mood, Ali H — Sirona Medical Technologies, INC.
- Study coordinator: Haghighi-Mood, Ali H
Related research
Other NIH-funded projects on the same topics.
-
Improving cardiac ablation procedures with advanced energy delivery technology
This study is looking to improve a heart treatment called catheter ablation for people with irregular heartbeats by creating a new device that delivers energy more precisely, making the procedure safer and more effective for patients.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.