NIH-funded research R01 grant

MRI-guided robotic catheter to improve treatment for atrial fibrillation

Official title: Improved arrhythmia ablation via MR-guided robotic catheterization and multimodal clinician feedback

Funded at Georgia Institute of Technology · NIH-11307065 · Data updated 2026-11-12

This project builds an MRI-compatible robotic catheter and real-time feedback system to help doctors create more complete, lasting ablation lesions for people with atrial fibrillation.

More Arrhythmia research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionGeorgia Institute of Technology
NIH-funded
Lab location1 site (Atlanta, United States)
Project startJune 26, 2023
Project endMarch 31, 2027
Funding year2026
Award (this year)$634,755
NIH project number5R01EB034359-04
Project IDNIH-11307065 on NIH RePORTER

Who could benefit from this research

Could help

People with symptomatic atrial fibrillation who are candidates for catheter radiofrequency ablation and willing to consider an MRI-guided procedure would be the most appropriate candidates.

Less likely to help

People who cannot undergo MRI (for example, due to incompatible implants), who have AF types not treated with RFA, or who require different therapies may not benefit from this approach.

What this research studies

The team is developing an MRI-compatible robotic catheter and a navigation feedback system designed to guide the catheter precisely during radiofrequency ablation for atrial fibrillation. The system combines MRI imaging, catheter tracking, and contact-force feedback to find gaps and ensure continuous lesion formation. Developers will test the hardware and software in preclinical settings and refine the system toward use during actual procedures. If it works as intended, the approach aims to reduce gaps that cause AF to come back.

Why it matters

Potential benefit: Could reduce AF recurrence and the need for repeat ablation by enabling more complete and durable heart lesions.

How similar studies have gone: Early MRI-guided cardiac intervention and robotic catheter work has shown promise in preclinical and pilot settings, but integrating continuous intraoperative MRI, robotic navigation, and lesion imaging is a novel combination not yet proven in routine human care.

Where this research is happening

  • Georgia Institute of Technology
    Atlanta, United States
    Active

Researchers

  • Principal investigator: Chen, Yue — Georgia Institute of Technology
  • Study coordinator: Chen, Yue

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.