MRI brain network scans to predict thinking and memory problems after stroke
Stroke Connectome MRI Biomarkers for VCID Risk Assessment
This project uses advanced MRI brain-connectivity scans plus health and neighborhood information to spot who may develop thinking and memory problems after a stroke.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-11324215 on NIH RePORTER |
What this research studies
You would have detailed MRI scans that map how different parts of your brain connect, plus tests of thinking and memory and information about your health and neighborhood. The team combines measures of vascular risk, baseline brain and cognitive health, and where you live using a neighborhood disadvantage map. They use cutting-edge connectome MRI, network neuroscience methods, and machine learning to find patterns linked to post-stroke cognitive decline. The project aims to include people from underrepresented groups and both rural and urban communities.
Who could benefit from this research
Good fit: Adults who have had a stroke and are willing to undergo MRI scans, cognitive testing, and share health and neighborhood information—especially those from underrepresented racial/ethnic and socioeconomic groups.
Not a fit: People without a history of stroke or those who cannot have MRI scans (for example, due to incompatible implants) are unlikely to benefit directly from participation.
Why it matters
Potential benefit: If successful, this work could help identify stroke survivors at high risk for vascular-related cognitive decline earlier so they can get closer monitoring or targeted prevention efforts.
How similar studies have performed: Previous research has linked MRI and vascular risk factors to post-stroke cognitive problems, but combining connectome MRI, neighborhood disadvantage mapping, and machine learning is a relatively new and innovative approach.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Nair, Veena a — University of Wisconsin-Madison
- Study coordinator: Nair, Veena a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.