MRI-based biomarkers to guide diagnosis, prognosis, and treatment monitoring
Official title: MRI Resource for Physiologic, Metabolic and Anatomic Biomarkers
Funded at Hugo W. Moser Res Inst Kennedy Krieger · NIH-11334982 · Data updated 2026-11-12
This project develops new noninvasive MRI biomarkers that could help doctors diagnose conditions, predict how they will progress, and monitor how well treatments work.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Hugo W. Moser Res Inst Kennedy Krieger NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | July 1, 2021 |
| Project end | June 30, 2031 |
| Funding year | 2026 |
| Award (this year) | $1,719,437 |
| NIH project number | 2P41EB031771-06 |
| Project ID | NIH-11334982 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are patients with conditions where MRI biomarkers could inform diagnosis, prognosis, or treatment decisions in the future.
✕Less likely to help
Patients without diseases where MRI biomarkers are informative or where imaging access is limited may see no direct benefit.
What this research studies
Researchers will design and test MRI-based biomarkers that act like in vivo biopsies, aiming to provide objective, reproducible measures of disease state. The work focuses on creating candidate imaging markers that correlate with clinical outcomes and can be used to guide trial designs and regulatory decisions. It will not involve a clinical trial itself but will lay the groundwork for future patient-facing biomarker use and decision-making. The effort emphasizes designing, testing, and validating MRI metrics before they are used in patient care or regulatory submissions.
Why it matters
Potential benefit: If successful, patients could receive more precise diagnoses and tailored treatment plans based on MRI biomarkers.
How similar studies have gone: Previous imaging biomarker work has shown promise in other diseases, but this project focuses on developing new MRI-based markers for broader clinical use.
Where this research is happening
-
Hugo W. Moser Res Inst Kennedy Krieger
Baltimore, United States Active
Researchers
- Principal investigator: Van Zijl, Peter Cm — Hugo W. Moser Res Inst Kennedy Krieger
- Study coordinator: Van Zijl, Peter Cm
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.