MPower Hub: a web program to help adults manage type 2 diabetes with glucose and activity data
Official title: T4/T3 Therapy in Hypothyroidism
Funded at University of Pennsylvania · NIH-11296941 · Data updated 2026-11-12
This project helps adults with type 2 diabetes use continuous glucose and activity tracker data alongside goal-setting tools to improve daily diabetes self-care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | April 15, 2024 |
| Project end | March 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $325,000 |
| NIH project number | 5R01DK137207-03 |
| Project ID | NIH-11296941 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults (21+) with type 2 diabetes who use or are willing to use a continuous glucose monitor and an activity tracker and want support with daily self-management.
✕Less likely to help
People without type 2 diabetes, those unwilling to use wearable glucose or activity devices, or those seeking only medication changes are unlikely to benefit from this program.
What this research studies
You would connect your continuous glucose monitor and activity tracker to a web platform that shows easy-to-understand visualizations of your data. The platform combines those visuals with behavior-change techniques like goal setting, action planning, and prompts to increase motivation. You will report medication and self-care behaviors and choose personal goals based on your own data. The team will refine the program and test how well it supports adults with type 2 diabetes.
Why it matters
Potential benefit: If successful, the program could help people stick to healthier daily habits and lower blood glucose, reducing the risk of diabetes complications.
How similar studies have gone: Previous digital coaching and continuous-glucose-monitor programs have shown promise for improving behaviors and glucose control, though this specific combination of personalized visualizations and structured action-planning is relatively new.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Cappola, Anne R — University of Pennsylvania
- Study coordinator: Cappola, Anne R
Related research
Other NIH-funded projects on the same topics.
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Discontinuing low-dose levothyroxine in older adults with subclinical hypothyroidism
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New approaches to treating hypothyroidism with LT4/LT3 therapy
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Better Ways to Treat Hypothyroidism
This project looks for the best way to combine two thyroid hormones, LT4 and LT3, to help people with hypothyroidism feel better and reduce heart risks.
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Investigating the effectiveness of combined T4 and T3 therapy for hypothyroidism
This study is looking into how a combination of two thyroid hormones, LT4 and LT3, might help people with hypothyroidism feel better, especially since some still have symptoms even while taking the usual treatment.
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Improving care for patients with hypothyroidism using real-world data
This study is looking at how well people with hypothyroidism are treated over time and how their thyroid hormone levels affect heart health, so if you're living with this condition, your health data could help us find better ways to manage it!
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New treatments for hypothyroidism
This study is looking at new ways to treat hypothyroidism by testing a combination of two thyroid hormones to see how they work together, and it's for people who want better options for managing their condition.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.