Monitoring uric acid levels in sweat to improve gout treatment
Cutaneous uric acid and metabolite monitoring to improve individual response to pharmaceutical and dietary treatment in patients with gout
This study is testing a new skin patch that can check your uric acid levels through your sweat, helping you see how your diet affects your gout in real-time, and it’s looking for people to join a 10-week trial to see how well it works.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | California Institute of Technology NIH-funded |
| Lab location | 1 site (Pasadena, United States) |
| Project ID | NIH-10642949 on NIH RePORTER |
What this research studies
This research investigates a new method for monitoring uric acid levels in patients with gout using a non-invasive skin patch that detects uric acid in sweat. The goal is to provide patients with real-time feedback on their uric acid levels before and after meals, which may help them make better dietary choices and adhere to their medication regimens. The study will also explore the impact of monitoring additional metabolites and nutrients to enhance patient outcomes. Participants will be involved in a 10-week trial to assess the effectiveness of this monitoring system.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with gout who are either currently on urate-lowering therapy or not receiving treatment.
Not a fit: Patients who do not have gout or hyperuricemia may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved management of gout through better dietary and medication adherence.
How similar studies have performed: Previous research has shown promise in using non-invasive monitoring techniques for metabolic conditions, suggesting potential success for this novel approach.
Where this research is happening
Pasadena, United States
- California Institute of Technology — Pasadena, United States (Active)
Researchers
- Principal investigator: Gao, Wei — California Institute of Technology
- Study coordinator: Gao, Wei
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.