Monitoring therapy response in Alzheimer's disease using advanced imaging techniques
Diffusion and Functional MRI Monitoring of Therapy Response in Alzheimer’s Disease Mouse Model
This study is looking at new ways to take pictures of the brain in mice to see how Alzheimer's disease changes it over time, which could help us find better treatments and understand the disease better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical University of South Carolina NIH-funded |
| Lab location | 1 site (Charleston, United States) |
| Project ID | NIH-11095980 on NIH RePORTER |
What this research studies
This research investigates new imaging methods to monitor the progression of Alzheimer's disease (AD) in a mouse model. It focuses on using diffusion MRI and functional MRI to detect early changes in brain structure and function that are associated with AD. By identifying these changes at an early stage, the research aims to improve the assessment of potential therapies and understand the underlying causes of the disease. The study utilizes advanced imaging techniques that are more sensitive than traditional methods, allowing for better tracking of disease progression.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with early signs of Alzheimer's disease or those at high risk for developing the condition.
Not a fit: Patients with advanced Alzheimer's disease or those who do not exhibit early symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for early detection and monitoring of Alzheimer's disease, potentially enhancing treatment outcomes.
How similar studies have performed: Previous studies have shown promise in using advanced imaging techniques for monitoring Alzheimer's disease, indicating that this approach could be effective.
Where this research is happening
Charleston, United States
- Medical University of South Carolina — Charleston, United States (Active)
Researchers
- Principal investigator: Jensen, Jens H — Medical University of South Carolina
- Study coordinator: Jensen, Jens H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.