Monitoring the safety of antipsychotic medications during pregnancy
Active Surveillance of the Safety of Antipsychotic Medications in Pregnancy
This study is looking into how safe antipsychotic medications are for pregnant women and their babies, using a new method to track any potential risks, so that moms can get the best care during pregnancy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11057614 on NIH RePORTER |
What this research studies
This research investigates the safety of antipsychotic medications for pregnant women, addressing significant gaps in current knowledge. It aims to develop a new method called TreeScan to actively monitor and evaluate the effects of these medications on both mothers and their babies. By analyzing large healthcare data, the study seeks to provide timely evidence on potential risks associated with these drugs, ensuring that women receive safe and effective treatment during pregnancy. The approach will focus on a wide range of maternal and fetal outcomes to better inform clinical decisions.
Who could benefit from this research
Good fit: Ideal candidates for this research include pregnant women who are currently prescribed antipsychotic medications or are considering such treatment for mental health conditions.
Not a fit: Patients who are not pregnant or those who do not require antipsychotic medications may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer treatment options for pregnant women with mental health conditions, ultimately improving maternal and fetal health outcomes.
How similar studies have performed: Previous research has shown promise in using cohort studies for drug safety surveillance, but the TreeScan method represents a novel approach that has not been widely tested.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Huybrechts, Krista F — Brigham and Women's Hospital
- Study coordinator: Huybrechts, Krista F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.