Monitoring stomach and breathing viruses in children

IP21-002, US Enhanced Surveillance Network to Assess Burden, Natural History, and Effectiveness of Vaccines to Prevent Enteric and Respiratory Viruses in Children

NIH-funded research Children's Mercy Hosp (Kansas City, Mo) · NIH-11138402

This program watches how often children get diarrheal and respiratory infections and checks how well vaccines protect them.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionChildren's Mercy Hosp (Kansas City, Mo) NIH-funded
Lab location1 site (Kansas City, United States)
Project IDNIH-11138402 on NIH RePORTER

What this research studies

If you join, the team will interview you, review your child's medical record, and collect stool and respiratory specimens to test for many gut and breathing viruses. Children seen in the emergency department or admitted to Children’s Mercy with acute gastroenteritis or respiratory illness can be enrolled, and healthy children coming for well visits will be enrolled as comparison controls. The study links vaccine records (like flu, rotavirus, COVID-19, and future vaccines) with lab results to see which infections occur in vaccinated and unvaccinated children. The program also tracks rare outcomes such as acute flaccid myelitis to better describe how often and how severely they happen.

Who could benefit from this research

Good fit: Ideal participants are children in the Kansas City area seen at Children’s Mercy for acute gastroenteritis or respiratory illness, or healthy children attending well-child visits as controls.

Not a fit: Adults, children not receiving care at the participating hospital network, or those unwilling to provide samples or vaccine records are unlikely to benefit directly from participation.

Why it matters

Potential benefit: Results could show which vaccines are working in the community and help guide stronger protection for children.

How similar studies have performed: This builds on the long-running Kansas City New Vaccine Surveillance Network and other surveillance programs that have successfully tracked infection trends and vaccine impact.

Where this research is happening

Kansas City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.