Monitoring stomach and breathing viruses in children
Official title: IP21-002, US Enhanced Surveillance Network to Assess Burden, Natural History, and Effectiveness of Vaccines to Prevent Enteric and Respiratory Viruses in Children
Funded at Children's Mercy Hosp (Kansas City, Mo) · NIH-11138402 · Data updated 2026-11-12
This program watches how often children get diarrheal and respiratory infections and checks how well vaccines protect them.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Mercy Hosp (Kansas City, Mo) NIH-funded |
| Lab location | 1 site (Kansas City, United States) |
| Project start | September 1, 2021 |
| Project end | August 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $2,000,000 |
| NIH project number | 5U01IP001154-05 |
| Project ID | NIH-11138402 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal participants are children in the Kansas City area seen at Children’s Mercy for acute gastroenteritis or respiratory illness, or healthy children attending well-child visits as controls.
✕Less likely to help
Adults, children not receiving care at the participating hospital network, or those unwilling to provide samples or vaccine records are unlikely to benefit directly from participation.
What this research studies
If you join, the team will interview you, review your child's medical record, and collect stool and respiratory specimens to test for many gut and breathing viruses. Children seen in the emergency department or admitted to Children’s Mercy with acute gastroenteritis or respiratory illness can be enrolled, and healthy children coming for well visits will be enrolled as comparison controls. The study links vaccine records (like flu, rotavirus, COVID-19, and future vaccines) with lab results to see which infections occur in vaccinated and unvaccinated children. The program also tracks rare outcomes such as acute flaccid myelitis to better describe how often and how severely they happen.
Why it matters
Potential benefit: Results could show which vaccines are working in the community and help guide stronger protection for children.
How similar studies have gone: This builds on the long-running Kansas City New Vaccine Surveillance Network and other surveillance programs that have successfully tracked infection trends and vaccine impact.
Where this research is happening
-
Children's Mercy Hosp (Kansas City, Mo)
Kansas City, United States Active
Researchers
- Principal investigator: Selvarangan, Rangaraj — Children's Mercy Hosp (Kansas City, Mo)
- Study coordinator: Selvarangan, Rangaraj
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.